TAK1-IN-5

MedChem Express

TAK1-IN-5

14

Research Use Only

C22H24N6O

388.47

TAK1-IN-5 (Compound 26) is an inhibitor of the transforming growth factor-beta activated kinase (TAK1) with an IC50 value of 55 nM. TAK1-IN-5 can inhibit the growth of MPC-11 and H929 cells with a GI50 lower than 30 nM. TAK1-IN-5 can be used in the study of multiple myeloma [1].

CC1CN(CC(O1)C)C2=NN3C(C4=CC5=C(NN=C5C6CC6)C=C4)=CN=C3C=C2

12352200