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CgoaEGY7Tr2ENj1_AAAAAHGcA_w166.png
CgoaEGY7Tr2ENj1_AAAAAHGcA_w166.png
CgoaEGY7Tr2ENj1_AAAAAHGcA_w166.png

TAK1/MAP4K2 inhibitor 1

Research Use Only
T10444
TargetMol Chemicals
CAS Number1315330-11-0
Product group Chemicals
Molecular Weight552.59
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TAK1/MAP4K2 inhibitor 1
  • Delivery Days Customer
    14
  • CAS Number
    1315330-11-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    TAK1/MAP4K2 inhibitor 1
  • Molecular Formula
    C29H31F3N6O2
  • Molecular Weight
    552.59
  • Scientific Description
    TAK1/MAP4K2 inhibitor 1 is a potent dual inhibitor of TGFbèta-activated kinase 1 (TAK1) and MAP4K2 (IC50s: 41.1 nM and 18.2 nM).
  • Shelf life instruction
    3 years
  • SMILES
    O(C1=C2C(NC(C)=C2)=NC=N1)C3=CC(C(NC4=CC(C(F)(F)F)=C(CN5CCN(CC)CC5)C=C4)=O)=CC=C3C
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Tan L, et al. Discovery of type II inhibitors of TGFbèta-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). J Med Chem. 2015 Jan 8;58(1):183-96.
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