Talmapimod [309913-83-5]

TargetMol Chemicals

Talmapimod [309913-83-5]

9

309913-83-5

Chemical

Research Use Only

Talmapimod

C27H30ClFN4O3

513

Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38alpha inhibitor with IC50 values of 9 nM for p38alpha and 90 nM for p38beta. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.

3 years

C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C

-20°C

12352200