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Talmapimod (hydrochloride )

HY-10406A
MedChem Express
CAS Number309915-12-6
Product group Chemicals
Molecular Weight549.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Talmapimod (hydrochloride ) [309915-12-6]
  • Delivery Days Customer
    10
  • CAS Number
    309915-12-6
  • Certification
    Research Use Only
  • Molecular Formula
    C27H31Cl2FN4O3
  • Molecular Weight
    549.46
  • Scientific Description
    Talmapimod (SCIO-469) hydrochloride is an orally active, selective, and ATP-competitive p38alpha inhibitor with an IC 50 of 9 nM. Talmapimod hydrochloride shows about 10-fold selectivity over p38beta, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs [1] [2] [3] .
  • SMILES
    O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3[C@H](C)CN(CC4=CC=C(F)C=C4)[C@@H](C)C3)=O)C(Cl)=C2)=O.[H]Cl
  • UNSPSC
    12352200