Tamoxifen-d3 (hydrochloride)
HY-13757S
Overview
- SupplierMedChem Express
- Product NameTamoxifen-d3 (hydrochloride)
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity98.99
- Molecular FormulaC26H27D3ClNO
- Molecular Weight410.99
- Scientific DescriptionTamoxifen-d3 hydrochloride is deuterated labeled Tamoxifen (Citrate) (HY-13757). Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[1][2][3].Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 microM and 1.8 microM, respectively[5]. Tamoxifen Citrate activates autophagy and induces apoptosis[4].Tamoxifen Citrate also can induce gene knockout of CreER(T2) transgenic mouse[6].
- SMILESCC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C([2H])([2H])[2H])C)C=C2)\C3=CC=CC=C3.Cl
- Storage Instruction-20°C
- UNSPSC12131703