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Tamoxifen-d3 (hydrochloride)

HY-13757S
MedChem Express
Estimated Purity98.99
Product group Chemicals
Molecular Weight410.99
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tamoxifen-d3 (hydrochloride)
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    98.99
  • Molecular Formula
    C26H27D3ClNO
  • Molecular Weight
    410.99
  • Scientific Description
    Tamoxifen-d3 hydrochloride is deuterated labeled Tamoxifen (Citrate) (HY-13757). Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[1][2][3].Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 microM and 1.8 microM, respectively[5]. Tamoxifen Citrate activates autophagy and induces apoptosis[4].Tamoxifen Citrate also can induce gene knockout of CreER(T2) transgenic mouse[6].
  • SMILES
    CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C([2H])([2H])[2H])C)C=C2)\C3=CC=CC=C3.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12131703