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TAO Kinase inhibitor 2 [850467-77-5]

Research Use Only
T77501
TargetMol Chemicals
Estimated Purity98.73%
Product group Chemicals
Molecular Weight400.47
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TAO Kinase inhibitor 2 [850467-77-5]
  • Delivery Days Customer
    4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    TAO Kinase inhibitor 2
  • Estimated Purity
    98.73%
  • Molecular Formula
    C25H24N2O3
  • Molecular Weight
    400.47
  • Scientific Description
    TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
  • Shelf life instruction
    3 years
  • SMILES
    N(C(CNC(=O)C1=CC=C(OC2=CC=CC=C2)C=C1)=O)C3C=4C(CCC3)=CC=CC4
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies. Giacomini C et al., 2018 May 7, Acta Neuropathol Commun
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