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TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST)

Research Use Only
TMPY-04399
TargetMol Chemicals
Molecular Weight74.3 kDa (predicted); 85 kDa (reducing conditions)
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    74.3 kDa (predicted); 85 kDa (reducing conditions)
  • Scientific Description
    Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each others functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains one protein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200