Tapasin antibody

GeneTex

Tapasin antibody

9

IP: Use at a dilution of 1/100. WB: Use at a dilution of 1/1000. Detects a band of approximately 48 kDa. Optimal dilutions/concentrations should be determined by the end user.

ImmunoPrecipitation, Western Blot

Research Use Only

Polyclonal

Unconjugated

TAPBP

TAP binding protein

NGS17; NGS-17; TAP binding protein (tapasin); TAPA; tapasin; TAP-associated protein; TPN; TPSN

Rabbit

IgG

Tapasin

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Bovine, Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203