TARDBP Polyclonal Antibody

Reddot Biotech

TARDBP Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

TARDBP

TAR DNA binding protein

ALS10; TAR DNA-binding protein 43; TAR DNA-binding protein-43; TDP-43

Rabbit

IgG

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Human, Mouse, Rat

-20°C

12352203