tat-nr2b9c

Selleck Chemicals

tat-nr2b9c [500992-11-0]

9

Research Use Only

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Tat-NR2B9c (Tat-NR2Bct, NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively, and disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 microM and 8 microM, respectively, also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.

-20°C

12352200