Tau antibody
GTX112981
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAPT
Overview
- SupplierGeneTex
- Product NameTau antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.12 mg/ml
- ConjugateUnconjugated
- Gene ID4137
- Target nameMAPT
- Target descriptionmicrotubule associated protein tau
- Target synonymsDDPAC, FTD1, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, Tau-PHF6, tau-40, microtubule-associated protein tau, G protein beta1/gamma2 subunit-interacting factor 1, PHF-tau, Tau-derived paired helical filament hexapeptide, neurofibrillary tangle protein, paired helical filament-tau, protein phosphatase 1, regulatory subunit 103
- HostRabbit
- IsotypeIgG
- Protein IDP10636
- Protein NameMicrotubule-associated protein tau
- Scientific DescriptionThis gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chang YL, Yang CC, Huang YY, et al. The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation. BMC Biol. 2023,21(1):293. doi: 10.1186/s12915-023-01798-6Read this paper
- Espinosa-Jiménez T, Cano A, Sánchez-López E, et al. A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet. Cell Biosci. 2023,13(1):52. doi: 10.1186/s13578-023-01000-yRead this paper
- Chen TF, Lee SH, Zheng WR, et al. White matter pathology in alzheimer's transgenic mice with chronic exposure to low-level ambient fine particulate matter. Part Fibre Toxicol. 2022,19(1):44. doi: 10.1186/s12989-022-00485-8Read this paper
- Katiyar P, Banerjee S, Nathani S, et al. Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in Neuro-2a cells. Curr Res Toxicol. 2022,3:100072. doi: 10.1016/j.crtox.2022.100072Read this paper
- Lee SH, Chen YH, Chien CC, et al. Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model. PLoS One. 2021,16(8):e0254587. doi: 10.1371/journal.pone.0254587Read this paper
- Rodríguez-Cruz F, Torres-Cruz FM, Monroy-Ramírez HC, et al. Fragmentation of the Golgi Apparatus in Neuroblastoma Cells Is Associated with Tau-Induced Ring-Shaped Microtubule Bundles. J Alzheimers Dis. 2018,65(4):1185-1207. doi: 10.3233/JAD-180547Read this paper









