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Tau antibody

GTX112981
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAPT
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Overview

  • Supplier
    GeneTex
  • Product Name
    Tau antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.12 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4137
  • Target name
    MAPT
  • Target description
    microtubule associated protein tau
  • Target synonyms
    DDPAC; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPTL; microtubule-associated protein tau; MSTD; MTBT1; MTBT2; neurofibrillary tangle protein; paired helical filament-tau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; TAU; tau-40
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP10636
  • Protein Name
    Microtubule-associated protein tau
  • Scientific Description
    This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation.
    Read more
  • A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimers disease exacerbated with high fat diet.
    Read more
  • White matter pathology in alzheimers transgenic mice with chronic exposure to low-level ambient fine particulate matter.
    Read more
  • Triclosan-induced neuroinflammation develops caspase-independent and TNF-alpha signaling pathway associated necroptosis in Neuro-2a cells. Katiyar P et al., 2022, Curr Res Toxicol
    Read more
  • Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimers disease mouse model. Lee SH et al., 2021, PLoS One
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  • Fragmentation of the Golgi Apparatus in Neuroblastoma Cells Is Associated with Tau-Induced Ring-Shaped Microtubule Bundles. Rodriguez-Cruz F et al., 2018, J Alzheimers Dis
    Read more