IHC-P analysis of mouse brain tissue using GTX24864 Tau (phospho Ser199/Ser202) antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:20
IHC-P analysis of mouse brain tissue using GTX24864 Tau (phospho Ser199/Ser202) antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:20
Tau (phospho Ser199/Ser202) antibody
GTX24864
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAPT
Overview
- SupplierGeneTex
- Product NameTau (phospho Ser199/Ser202) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. ICC/IF: 1microg/mL. IHC-P: 1:10-1:100. FACS: 3-5 microg/million cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4137
- Target nameMAPT
- Target descriptionmicrotubule associated protein tau
- Target synonymsDDPAC; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPTL; microtubule-associated protein tau; MSTD; MTBT1; MTBT2; neurofibrillary tangle protein; paired helical filament-tau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; TAU; tau-40
- HostRabbit
- IsotypeIgG
- Protein IDP10636
- Protein NameMicrotubule-associated protein tau
- Scientific DescriptionThis gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- White matter pathology in alzheimers transgenic mice with chronic exposure to low-level ambient fine particulate matter.Read more
- Microtube Array Membrane Encapsulated Cell Therapy: A Novel Platform Technology Solution for Treatment of Alzheimers Disease. Chen SM et al., 2022 Jun 20, Int J Mol SciRead more
- Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimers disease mouse model. Lee SH et al., 2021, PLoS OneRead more
- Activation of G-protein coupled estrogen receptor 1 improves early-onset cognitive impairment via PI3K/Akt pathway in rats with traumatic brain injury. Wang ZF et al., 2017 Jan 22, Biochem Biophys Res CommunRead more
- Overactivation of NR2B-containing NMDA receptors through entorhinal-hippocampal connection initiates accumulation of hyperphosphorylated tau in rat hippocampus after transient middle cerebral artery occlusion. Xu CS et al., 2015 Aug, J NeurochemRead more
- The role of heat shock protein 70 in the protective effect of YC-1 on beta-amyloid-induced toxicity in differentiated PC12 cells. Tsai YC et al., 2013, PLoS OneRead more