TAZ Polyclonal Antibody

Reddot Biotech

TAZ Polyclonal Antibody

5

ImmunoFluorescence

Research Use Only

1 mg/ml

Unconjugated

WWTR1

WW domain containing transcription regulator 1

TAZ; transcriptional co-activator with PDZ-binding motif; WW domain-containing transcription regulator protein 1

Rabbit

IgG

TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma. TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial,Aeimesenchymal transition (EMT). TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1.

Human, Mouse

-20°C

12352203