Bio-Connect

TBK1 Polyclonal Antibody

RD82699A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
TargetTBK1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    TBK1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID29110
  • Target name
    TBK1
  • Target description
    TANK binding kinase 1
  • Target synonyms
    FTDALS4; IIAE8; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine-protein kinase TBK1; T2K
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203