TBOPP

Selleck Chemicals

TBOPP

9

Research Use Only

TBOPP is a selective inhibitor of dedicator of cytokinesis (DOCK1, Dock180) that inhibits DOCK1-mediated Rac activation with IC50 of 8.4 muM. TBOPP binds to the DOCK1 DHR-2 domain with Kd of 7.1 muM. TBOPP exhibits anti-tumor activity.

12352200