
Western blot analysis of extracts from 293 cells, using TBP antibody.
TBP Antibody
CSB-PA276652
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTBP
Overview
- SupplierCusabio
- Product NameTBP Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6908
- Target nameTBP
- Target descriptionTATA-box binding protein
- Target synonymsGTF2D; GTF2D1; HDL4; SCA17; TATA sequence-binding protein; TATA-box binding protein N-terminal domain; TATA-box factor; TATA-box-binding protein; TFIID; transcription initiation factor TFIID TBP subunit
- HostRabbit
- IsotypeIgG
- Protein IDP20226
- Protein NameTATA-box-binding protein
- Scientific DescriptionGeneral transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Peterson M.G., Science 248:1625-1630(1990). Mungall A.J., Nature 425:805-811(2003). Gangloff Y.G., Mol. Cell. Biol. 21:5109-5121(2001).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203