TBP Monoclonal Antibody

Reddot Biotech

TBP Monoclonal Antibody

5

Western Blot

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

TBP

TATA-box binding protein

GTF2D; GTF2D1; HDL4; SCA17; TATA sequence-binding protein; TATA-box binding protein N-terminal domain; TATA-box factor; TATA-box-binding protein; TFIID; transcription initiation factor TFIID TBP subunit

Mouse

IgG

This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.

Human, Mouse, Rat

-20°C

12352203