TBX1 Polyclonal Antibody

Reddot Biotech

TBX1 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.7 mg/ml

Unconjugated

TBX1

T-box transcription factor 1

brachyury; CAFS; CATCH22; CTHM; DGCR; DGS; DORV; T-box 1 transcription factor C; T-box transcription factor TBX1; TBX1C; Testis-specific T-box protein; TGA; VCF; VCFS

Rabbit

IgG

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Human

-20°C

12352203