TCF4 Polyclonal Antibody

Reddot Biotech

TCF4 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot

Research Use Only

1 mg/ml

Unconjugated

TCF4

transcription factor 4

bHLHb19; CDG2T; class B basic helix-loop-helix protein 19; E2-2; FECD3; immunoglobulin transcription factor 2; ITF2; ITF-2; PTHS; SEF2; SEF-2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; SL3-3 enhancer factor 2; TCF-4; transcription factor 4

Rabbit

IgG

This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box (E-box) binding site (CANNTG) - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

Human, Mouse, Rat

-20°C

12352203