TCS-OX2-29

MedChem Express

TCS-OX2-29 [372523-75-6]

10

372523-75-6

Research Use Only

99.55

C23H31N3O3

397.51

TCS-OX2-29 is a potent, high affinities and selective orexin-2 receptor (OX2R) antagonist with an IC50 value of 40 nM and a pKI value of 7.5. TCS-OX2-29 displays ~250-fold selectivity for OX2 over OX1[1][2].

CC(C)(C)[C@H](NCC1=CC=NC=C1)C(N2CC3=C(C=C(OC)C(OC)=C3)CC2)=O

-20°C,2°C to 8°C

12352200