TCS-OX2-29 (hydrochloride)

MedChem Express

TCS-OX2-29 (hydrochloride)

10

C23H32ClN3O3

433.97

TCS-OX2-29 (hydrochloride) is a potent, high affinities and selective orexin-2 receptor (OX 2 R) antagonist with an IC 50 value of 40 nM and a pK I value of 7.5. TCS-OX2-29 displays ~250-fold selectivity for OX 2 over OX 1 [1] [2] .

CC(C)(C)[C@H](NCC1=CC=NC=C1)C(N2CC3=C(C=C(OC)C(OC)=C3)CC2)=O.[H]Cl

12352200