TDG antibody
ORB67223
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetTDG
Overview
- SupplierBiorbyt
- Product NameTDG antibody
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:1000-1:5000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6996
- Target nameTDG
- Target descriptionthymine DNA glycosylase
- Target synonymsG/T mismatch-specific thymine DNA glycosylase; hTDG
- HostRabbit
- Protein IDQ13569
- Protein NameG/T mismatch-specific thymine DNA glycosylase
- Scientific DescriptionRabbit polyclonal to TDG.G/T mismatch-specific thymine DNA glycosylase (TDG) belongs to the TDG/mug DNA glycosylasefamily. TDG removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bondbetween the sugar-phosphate backbone of DNA and the mispaired thymine. TDG also removesthymine from C/T and T/T mispairings with lower activity. In addition, TDG can remove uracil and 5-bromouracil from mispairings with guanine. TDG plays a central role in cellular defense againstgenetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203