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ProductsBack/TDG (C) Antibody, Rabbit Polyclonal

TDG (C) Antibody, Rabbit Polyclonal

ORB67224
Biorbyt
TargetTDG
Product group Antibodies
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Overview

  • Supplier
    Biorbyt
  • Product Name
    TDG antibody
  • Delivery Days Customer
    16
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Gene ID6996
  • Target name
    TDG
  • Target description
    thymine DNA glycosylase
  • Target synonyms
    G/T mismatch-specific thymine DNA glycosylase; hTDG
  • Protein IDQ13569
  • Protein Name
    G/T mismatch-specific thymine DNA glycosylase
  • Scientific Description
    Rabbit polyclonal to TDG.G/T mismatch-specific thymine DNA glycosylase (TDG) belongs to the TDG/mug DNA glycosylasefamily. TDG removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bondbetween the sugar-phosphate backbone of DNA and the mispaired thymine. TDG also removesthymine from C/T and T/T mispairings with lower activity. In addition, TDG can remove uracil and 5-bromouracil from mispairings with guanine. TDG plays a central role in cellular defense againstgenetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203