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ProductsBack/TDI-10229 [2810887-45-5]
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CgoaEWY7Pg-EarjXAAAAAOSWMX4685.png
CgoaEWY7Pg-EarjXAAAAAOSWMX4685.png

TDI-10229 [2810887-45-5]

Research Use Only
T64355
TargetMol Chemicals
Molecular Weight313.78
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TDI-10229 [2810887-45-5]
  • Delivery Days Customer
    4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    TDI-10229
  • Molecular Formula
    C16H16ClN5
  • Molecular Weight
    313.78
  • Scientific Description
    TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10), displaying nanomolar inhibition of sAC in both biochemical and cellular assays (IC50 = 195 nM). TDI-10229 exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Balbach M, et al. Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization [published online ahead of print, 2021 Aug 31]. Mol Hum Reprod. 2021;gaab054.
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