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TDO-IN-1

T61202
TargetMol Chemicals
CAS Number2490672-92-7
Product group Chemicals
Molecular Weight350.3
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TDO-IN-1
  • Delivery Days Customer
    9
  • CAS Number
    2490672-92-7
  • Category Supplier
    Chemical
  • Chemical Name
    TDO-IN-1
  • Molecular Formula
    C16H13F3N4O2
  • Molecular Weight
    350.3
  • Scientific Description
    TDO-IN-1 is an orally active, potent, and selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which inhibits indoleamine-2,3-dioxygenase.TDO-IN-1 has antitumor activity and is able to act by reversing local immune tolerance in tumor tissues.
  • Shelf life instruction
    3 years
  • SMILES
    N(CC1=C(N(=O)=O)C=C(C)C=C1)C2=C3C(=CC(C(F)(F)F)=C2)NN=C3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Huo C, et al. 4,6-Disubstituted-1H-Indazole-4-Amine derivatives with immune-chemotherapy effect and in vivo antitumor activity. Eur J Med Chem. 2022 Nov 5;241:114625.