Bio-Connect

TDP1 Polyclonal Antibody

RD267936A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman
TargetTDP1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    TDP1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID55775
  • Target name
    TDP1
  • Target description
    tyrosyl-DNA phosphodiesterase 1
  • Target synonyms
    tyr-DNA phosphodiesterase 1; tyrosyl-DNA phosphodiesterase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203