Tectol

MedChem Express

Tectol [24449-39-6]

10

24449-39-6

Research Use Only

99.72

C30H26O4

450.53

Tectol, isolated from Lippia sidoides, exhibits significant activity against human leukemia cell lines HL60 and CEM[1]. Tectol is a farnesyltransferase (FTase) inhibitor with IC50s of 2.09 and 1.73 microM for human and T. brucei FTase, respectively. Tectol inhibits drug-resistant strain of P. falciparum (FcB1) with an IC50 of 3.44 microM[1][2].

OC1=C(C=CC=C2)C2=C(O3)C(C=CC3(C)C)=C1C4=C(C=CC5(C)C)C(O5)=C6C(C=CC=C6)=C4O

2°C to 8°C

12352200