TEK Polyclonal Antibody

Reddot Biotech

TEK Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

Polyclonal

470 ug/ml

Unconjugated

TEK

TEK receptor tyrosine kinase

angiopoietin-1 receptor; CD202B; endothelial tyrosine kinase; GLC3E; TEK tyrosine kinase, endothelial; TIE2; TIE-2; tunica interna endothelial cell kinase; tyrosine kinase with Ig and EGF homology domains-2; tyrosine-protein kinase receptor TEK; tyrosine-protein kinase receptor TIE-2; VMCM; VMCM1

Rabbit

IgG

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Human, Mouse, Rat

-20°C

12352203