Tenofovir exalidex [911208-73-6]
T28946
CAS Number911208-73-6
Product group Chemicals
Estimated Purity99.54%
Molecular Weight569.72
Overview
- SupplierTargetMol Chemicals
- Product NameTenofovir exalidex
- Delivery Days Customer9
- CAS Number911208-73-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameTenofovir exalidex
- Estimated Purity99.54%
- Molecular FormulaC28H52N5O5P
- Molecular Weight569.72
- Scientific DescriptionTenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleoside/nucleotide analogs. It effectively inhibits all major HIV-1 and HIV-2 subtypes in fresh human PBMCs, as well as all evaluated HIV-1 strains in monocyte-derived macrophages, displaying EC50 values between 0.2 and 7.2 nM. Oral administration of CMX157 shows no apparent toxicity. Additionally, Tenofovir exalidex exhibits antiviral properties against HBV.
- Shelf life instruction3 years
- SMILESC([C@H](OCP(OCCCOCCCCCCCCCCCCCCCC)(=O)O)C)N1C=2C(N=C1)=C(N)N=CN2
- Storage Instruction-20°C
- UNSPSC12352200