More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Tenovin-6 [1011557-82-6]

Tenovin-6 [1011557-82-6]

T1853
LKT Laboratories
Estimated Purity≥98%
DownloadDatasheet
Product group Chemicals
€ 1.611,00
25 mg
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Tenovin-6 [1011557-82-6]
  • Delivery Days Customer
    7
  • Estimated Purity
    ≥98%
  • Format
    DMSO 98 mg/mL (215.55 mM); Water 98 mg/mL warmed (215.55 mM); Ethanol Insoluble
  • Scientific Description
    SIRT1/2 inhibitor, indirect p53 activator.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Ueno T, Endo S, Saito R, et al. The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-Fluorouracil and oxaliplatin in colon cancer cells. Oncol Res. 2014;21(3):155-64. PMID: 24512730. MacCallum SF, Groves MJ, James J, et al. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Sci Rep. 2013;3:1275. PMID: 23429453. Lain S, Hollick JJ, Campbell J, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63. PMID: 18455128. Brooks CL, Gu W. p53 Activation: a case against Sir. Cancer Cell. 2008 May;13(5):377-8. PMID: 18455119.