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ProductsBack/Territrem B [70407-20-4]
Chemical Structure
Chemical Structure
Chemical Structure

Territrem B [70407-20-4]

Research Use Only
AG-CN2-0142
AdipoGen Life Sciences
CAS Number70407-20-4
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight526.6
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Territrem B [70407-20-4]
  • Delivery Days Customer
    10
  • ADR Class
    6.1
  • CAS Number
    70407-20-4
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C29H34O9
  • Molecular Weight
    526.6
  • Scientific Description
    Chemical. CAS: 70407-20-4. Formula: C29H34O9. MW: 526.6. Synthetic. Originally isolated from Aspergillus terreus. Tremorgenic mycotoxin. Potent and specific, irreversible acetylcholinesterase (AChE) inhibitor. - Tremorgenic mycotoxin [1, 2]. Potent and specific, irreversible acetylcholinesterase (AChE) inhibitor [3-7].
  • SMILES
    COC1=CC(=CC(OC)=C1OC)C1=CC2=C(C[C@@]3(O)[C@@](C)(CC[C@@]4(O)C(C)(C)C=CC(=O)[C@]34C)O2)C(=O)O1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UN Number
    UN 3462
  • UNSPSC
    12352200

References

  • Territrems, tremorgenic mycotoxins of Aspergillus terreus: K.H. Ling, et al.; Appl. Environ. Microbiol. 37, 355 (1979)
  • Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem B' from Aspergillus terreus: F.C. Peng, et al.; Appl. Environ. Microbiol. 49, 721 (1985)
  • Effects of territrem-B on cholinergic responses of snail neuron: V.L. Arvanov, et al.; Neurosci. Lett. 152, 69 (1993)
  • Acetylcholinesterase inhibition by territrem B derivatives: F.C. Peng; J. Nat. Prod. 58, 857 (1995)
  • Territrems: Naturally Occurring Specific Irreversible Inhibitors of Acetylcholinesterase: J.W. Chen & K.H. Ling; J. Biomed. Sci. 3, 54 (1996)
  • Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. I. Screening, taxonomy, fermentation, isolation and biological activity: F. Kuno, et al.; J. Antibiot. 49, 742 (1996)
  • Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism: J.W. Chen, et al.; J. Biol. Chem. 274, 34916 (1999)