Western blot analysis of extracts from COLO205 cells, using AP-2 antibody.
Western blot analysis of extracts from COLO205 cells, using AP-2 antibody.
TFAP2A Antibody
CSB-PA178989
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTFAP2A
Overview
- SupplierCusabio
- Product NameTFAP2A Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7020
- Target nameTFAP2A
- Target descriptiontranscription factor AP-2 alpha
- Target synonymsactivating enhancer-binding protein 2-alpha; activator protein 2; AP-2; AP-2 transcription factor; AP-2alpha; AP2TF; BOFS; TFAP2; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2-alpha
- HostRabbit
- IsotypeIgG
- Protein IDP05549
- Protein NameTranscription factor AP-2-alpha
- Scientific DescriptionSequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5-GCCNNNGGC-3 and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602. TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064. Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768. Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203