Western blot analysis of extracts from K562 cells and A549 cells, using TFE3 antibody.
Western blot analysis of extracts from K562 cells and A549 cells, using TFE3 antibody.
TFE3 Antibody
CSB-PA827304
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetTFE3
Overview
- SupplierCusabio
- Product NameTFE3 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7030
- Target nameTFE3
- Target descriptiontranscription factor binding to IGHM enhancer 3
- Target synonymsbHLHe33; class E basic helix-loop-helix protein 33; RCCP2; RCCX1; TFEA; transcription factor E family, member A; transcription factor E3; transcription factor for IgH enhancer; transcription factor for immunoglobulin heavy-chain enhancer 3
- HostRabbit
- IsotypeIgG
- Protein IDP19532
- Protein NameTranscription factor E3
- Scientific DescriptionTranscription factor that specifically recognizes and binds E-box sequences (5-CANNTG-3). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. Clark J., Oncogene 15:2233-2239(1997). Sidhar S.K., Hum. Mol. Genet. 5:1333-1338(1996). Beckmann H., Genes Dev. 4:167-179(1990).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203