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ProductsBack/TG007 [719277-30-2]
Chemical Structure
Chemical Structure
Chemical Structure

TG007 [719277-30-2]

Research Use Only
AG-CR1-3666
AdipoGen Life Sciences
CAS Number719277-30-2
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Product group Chemicals
Estimated Purity>98%
Molecular Weight277.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    TG007 [719277-30-2]
  • Delivery Days Customer
    10
  • CAS Number
    719277-30-2
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Non-hazardous,Warning
  • Molecular Formula
    C14H15NO3S
  • Molecular Weight
    277.3
  • Scientific Description
    Chemical. CAS: 719277-30-2. Formula: C14H15NO3S. MW: 277.3. Synthetic. Prodrug form (acetylated derivative) of INDY (Prod. No. AG-CR1-3665). Cell permeable ATP-competitive DYRK1A and DYRK1B inhibitor. Inhibits phosphorylation of Tau-protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo. - Prodrug form (acetylated derivative) of INDY (Prod. No. AG-CR1-3665). Cell permeable ATP-competitive DYRK1A and DYRK1B inhibitor. Inhibits phosphorylation of Tau-protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo.
  • SMILES
    O=C(C)/C=C1SC2=CC=C(OC(C)=O)C=C2N\1CC
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A: Y. Ogawa, et al.; Nat. Commun. 1, 86 (2010)