TGFB1 Polyclonal Antibody
RD70286A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetTgfb1
Overview
- SupplierReddot Biotech
- Product NameTGFB1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID21803
- Target nameTgfb1
- Target descriptiontransforming growth factor, beta 1
- Target synonymsTgfb; Tgfb-1; TGFbeta; TGF-beta; TGFbeta1; TGF-beta1; transforming growth factor beta-1 proprotein
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203