More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/TGFbètaRI-IN-3
TGFbètaRI-IN-3

TGFbètaRI-IN-3

T9523
TargetMol Chemicals
CAS Number2763602-67-9
DownloadDatasheet
DownloadMSDS
Product group Chemicals
Molecular Weight465.57
Price on request
Packing Size
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TGFbètaRI-IN-3
  • Delivery Days Customer
    9
  • CAS Number
    2763602-67-9
  • Category Supplier
    Chemical
  • Chemical Name
    TGFbètaRI-IN-3
  • Molecular Formula
    C28H23N3O2S
  • Molecular Weight
    465.57
  • Scientific Description
    TGFbètaRI-IN-3 inhibits TGFbètaR1 with an IC 50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFbètaRI-IN-3 is a highly selective TGFbètaR1 inhibitor that has potential applications in immuno-oncology [1].
  • Shelf life instruction
    3 years
  • SMILES
    N(C=1C2=C(C=C(C=C2)C3=CC=C(S(C)(=O)=O)C=C3)N=CC1)C=4C=C(N=CC4)C5=CC(C)=CC=C5
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Kharbanda A, et al. Discovery of 4-aminoquinolines as highly selective TGFβR1 inhibitors with an attenuated MAP4K4 profile for potential applications in immuno-oncology [published online ahead of print, 2021 Aug 12]. Eur J Med Chem. 2021;225:113763.
    Read more