TH287 (hydrochloride) [1638211-05-8]
HY-16965A
CAS Number1638211-05-8
Product group Chemicals
Molecular Weight305.59
Overview
- SupplierMedChem Express
- Product NameTH287 (hydrochloride) [1638211-05-8]
- Delivery Days Customer10
- CAS Number1638211-05-8
- CertificationResearch Use Only
- Molecular FormulaC11H11Cl3N4
- Molecular Weight305.59
- Scientific DescriptionTH287 hydrochloride is a potent and selective inhibitor of MTH1, with an IC50 of 0.8 nM. TH287 hydrochloride is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 microM. TH287 hydrochloride could act as a chemotherapeutic agent for cancer research[1].
- SMILESNC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC)=N1.[H]Cl
- UNSPSC12352200