TH588

Selleck Chemicals

TH588 [1609960-31-7]

9

1609960-31-7

...

TH588 is a potent and selective MTH1 (NUDT1) inhibitor with IC50 of 5 nM. It has no relevant inhibition of any of the other tested proteins at 100 microM, although TH588 showed reasonable selectivity when tested on a much larger panel of 87 enzymes, GPCRs, kinases, ion channels and transporters at 10 microM.

-80°C

51202000