Thalidomide 4-ether-PEG2-azide

MedChem Express

Thalidomide 4-ether-PEG2-azide

14

Research Use Only

Thalidomide 4-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates ( E3 Ligase Ligand-Linker Conjugates ) for the synthesis of PROTACs [1] .

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