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Thalidomide-NH-C10-Boc

HY-161961
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Thalidomide-NH-C10-Boc
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Thalidomide-NH-C10-Boc (compound S20) is a conjugate of the E3 ubiquitinase ligand Thalidomide and PROTAC Linker , which can recruit Cereblon ubiquitinase. Thalidomide-NH-C10-Boc can couple the target protein ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, Thalidomide-NH-C10-Boc can couple with the ligand EP300/CBP ligand 2 (HY-161960) to produce the PROTAC molecule dCE-2 (HY-161958) [1] .
  • UNSPSC
    41116133