Thalidomide-NH-C4-NH2 (TFA) [2093387-50-7]

MedChem Express

Thalidomide-NH-C4-NH2 (TFA) [2093387-50-7]

10

2093387-50-7

Research Use Only

C19H21F3N4O6

458.39

Thalidomide-NH-C4-NH2 TFA (compound 29c) is an E3 ligase ligand-linker conjugate, and incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-NH-C4-NH2 TFA is used in PROTAC BRD2/BRD4 degrader-1 (HY-130612). PROTAC BRD2/BRD4 degrader-1 is a potent and selective BET protein BRD4 and BRD2 degrader[1].

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCN)=O.O=C(O)C(F)(F)F

41115800