Thalidomide-NH-(CH2)2-NH2 TFA

Biorbyt

Thalidomide-NH-(CH2)2-NH2 TFA [1957235-67-4]

10

1957235-67-4

Research Use Only

98.00%

C17H17F3N4O6

430.34

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

NCCNC1=C2C(=O)N(C3C(=O)NC(=O)CC3)C(=O)C2=CC=C1.OC(=O)C(F)(F)F

-20°C

12352200