Thalidomide-O-PEG2-propargyl [2098487-52-4]

TargetMol Chemicals

Thalidomide-O-PEG2-propargyl [2098487-52-4]

14

2098487-52-4

Chemical

Research Use Only

Thalidomide-O-PEG2-propargyl

C20H20N2O7

400.38

Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].

3 years

O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCOCCOCC#C)C3C2=O)CC1

-20°C

12352200