Theaflavin 3,3-digallate (Standard) [30462-35-2]

MedChem Express

Theaflavin 3,3-digallate (Standard) [30462-35-2]

9

30462-35-2

Research Use Only

C43H32O20

868.70

Theaflavin 3,3-digallate (Standard) is the analytical standard of Theaflavin 3,3-digallate. This product is intended for research and analytical applications. Theaflavin 3,3-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 microM. Theaflavin 3,3-digallat directly binds to ZIKVpro (Kd=8.86 microM) and inhibits ZIKV replication. Theaflavin 3,3-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1[1]. Theaflavin 3,3-digallate, the typical pigment in black tea, is a potent antitumor agent[2].

O=C(C1=CC(O)=C(C(O)=C1)O)O[C@H]2[C@H](OC3=CC(O)=CC(O)=C3C2)C4=C5C(C(C(O)=CC([C@@H]6[C@@H](CC7=C(O)C=C(O)C=C7O6)OC(C8=CC(O)=C(C(O)=C8)O)=O)=C5)=O)=C(C(O)=C4)O

41116135