Thiazole orange dimer YOYO 1

MedChem Express

Thiazole orange dimer YOYO 1

5

5 mM

97.00

C49H58I4N6O2

1270.64

Thiazole orange dimer YOYO 1 is a green fluorescent dye used for DNA staining. It belongs to the monomethine cyanine dye family and is a tetracationic homodimer of oxazole yellow (abbreviated as YO, hence the name YOYO), usually provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (lambdamax 458 nm; lambdamax 564 nm) has a very low fluorescence quantum yield, but after binding to double-stranded DNA through diintercalation, the fluorescence intensity is increased by 3200 times (lambdamax 489 nm; lambdamax 509 nm).

CN1C2=CC=CC=C2O/C1=C\C3=CC=[N+](C4=C3C=CC=C4)CCC[N+](CCC[N+](CCC[N+]5=CC=C(C6=C5C=CC=C6)/C=C7N(C8=C(O/7)C=CC=C8)C)(C)C)(C)C.[I-].[I-].[I-].[I-]

-20°C

41116134