Chemical Structure
Thioglycine [758-10-1]
AG-CR1-3530
Overview
- SupplierAdipoGen Life Sciences
- Product NameThioglycine [758-10-1]
- Delivery Days Customer10
- CAS Number758-10-1
- CertificationResearch Use Only
- Estimated Purity>98%
- Molecular FormulaC2H5NOS
- Molecular Weight91.1
- Scientific DescriptionChemical. CAS: 758-10-1. Formula: C2H5NOS. MW: 91.1. Synthetic. Non-toxic hydrogen sulfide (H2S) donor in vitro and in vivo. Stable under acidic and basic conditions but in the presence of bicarbonate liberates the gasotransmitter H2S and glycine. In cells it enhances cGMP formation and in mouse aortic rings promotes vasorelaxation. Cardiopotective agent. - Non-toxic hydrogen sulfide (H2S) donor in vitro and in vivo. Stable under acidic and basic conditions but in the presence of bicarbonate liberates the gasotransmitter H2S and glycine. In cells it enhances cGMP formation and in mouse aortic rings promotes vasorelaxation. Cardioprotective agent.
- SMILESNCC(S)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Characterization of thioglycine, a water-soluble hydrogen sulfide (H2S) donor: Z. Zhou, et al.; Vasc. Pharmacol. 56, 356 (2012)
- Thioglycine and L-thiovaline: biologically active H2S-donors: Z. Zhou, et al. Bioorg. Med. Chem. 20, 2675 (2012)
- Thioglycine, a slow-releasing H2S donor, exerts cardioprotection in anesthetized rabbits through activation of Akt kinase: S.I. Bibli, et al.; Eur. Heart J. 34 (Suppl. 1), P5535 (2013)
- Hydrogen sulfide (H2S) releasing agents: chemistry and biological applications: Y. Zhao, et al.; Chem. Commun. 50, 11788 (2014)