THK-5105 [1374107-46-6]

MedChem Express

THK-5105 [1374107-46-6]

10

1374107-46-6

Research Use Only

C20H21FN2O2

340.39

THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe[1].

OC(CF)COC1=CC=C2N=C(C3=CC=C(N(C)C)C=C3)C=CC2=C1

12131703