THK-5117
HY-101182
Molecular Weight326.36
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameTHK-5117
- Delivery Days Customer10
- Molecular FormulaC19H19FN2O2
- Molecular Weight326.36
- Scientific DescriptionTHK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a K i of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe [1] .
- SMILESOC(COC1=CC=C2N=C(C3=CC=C(NC)C=C3)C=CC2=C1)CF
- UNSPSC12352200