Bio-Connect

THK-5117

HY-101182
MedChem Express
Molecular Weight326.36
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    THK-5117
  • Delivery Days Customer
    10
  • Molecular Formula
    C19H19FN2O2
  • Molecular Weight
    326.36
  • Scientific Description
    THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a K i of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe [1] .
  • SMILES
    OC(COC1=CC=C2N=C(C3=CC=C(NC)C=C3)C=CC2=C1)CF
  • UNSPSC
    12352200