Thymidine Phosphorylase antibody [P-GF.44C]
GTX23151
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetTYMP
Overview
- SupplierGeneTex
- Product NameThymidine Phosphorylase antibody [P-GF.44C]
- Delivery Days Customer9
- Application Supplier NoteWestern Blotting: assay dependent. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 1 - 2microg / ml for 30 min at RT. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 55 kDa, which corresponds to the predicted molecular weight of Thymidine Phosphorylase. No special pretreatment is required for immuno-histochemical staining of formalin-fixed tissues
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDP-GF.44C
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID1890
- Target nameTYMP
- Target descriptionthymidine phosphorylase
- Target synonymsECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF, thymidine phosphorylase, gliostatin, tdRPase
- HostMouse
- IsotypeIgG1
- Protein IDP19971
- Protein NameThymidine phosphorylase
- Scientific DescriptionThis gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Gautheron J, Lima L, Akinci B, et al. Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes. BMC Med. 2022,20(1):95. doi: 10.1186/s12916-022-02296-2Read this paper
- Gajjar KK, Vora HH, Kobawala TP, et al. Deciphering the potential value of 5-fluorouracil metabolic enzymes in predicting prognosis and treatment response of colorectal cancer patients. Int J Biol Markers. 2018,33(2):180-188. doi: 10.1177/1724600817748539Read this paper


