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Thymidine Phosphorylase antibody [P-GF.44C]

GTX23151
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTYMP
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Overview

  • Supplier
    GeneTex
  • Product Name
    Thymidine Phosphorylase antibody [P-GF.44C]
  • Delivery Days Customer
    9
  • Application Supplier Note
    Western Blotting: assay dependent. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 1 - 2microg / ml for 30 min at RT. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 55 kDa, which corresponds to the predicted molecular weight of Thymidine Phosphorylase. No special pretreatment is required for immuno-histochemical staining of formalin-fixed tissues
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    P-GF.44C
  • Concentration
    2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1890
  • Target name
    TYMP
  • Target description
    thymidine phosphorylase
  • Target synonyms
    ECGF; ECGF1; gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; PDECGF; tdRPase; thymidine phosphorylase; TP
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP19971
  • Protein Name
    Thymidine phosphorylase
  • Scientific Description
    This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes. Gautheron J et al., 2022 Mar 28, BMC Med
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  • Deciphering the potential value of 5-fluorouracil metabolic enzymes in predicting prognosis and treatment response of colorectal cancer patients. Gajjar KK et al., 2018 May, Int J Biol Markers
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