Bio-Connect

Thymidine Phosphorylase antibody [P-GF.44C]

GTX23151
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetTYMP
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Thymidine Phosphorylase antibody [P-GF.44C]
  • Delivery Days Customer
    9
  • Application Supplier Note
    Western Blotting: assay dependent. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 1 - 2microg / ml for 30 min at RT. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 55 kDa, which corresponds to the predicted molecular weight of Thymidine Phosphorylase. No special pretreatment is required for immuno-histochemical staining of formalin-fixed tissues
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    P-GF.44C
  • Concentration
    2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1890
  • Target name
    TYMP
  • Target description
    thymidine phosphorylase
  • Target synonyms
    ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF, thymidine phosphorylase, gliostatin, tdRPase
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP19971
  • Protein Name
    Thymidine phosphorylase
  • Scientific Description
    This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Gautheron J, Lima L, Akinci B, et al. Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes. BMC Med. 2022,20(1):95. doi: 10.1186/s12916-022-02296-2
    Read this paper
  • Gajjar KK, Vora HH, Kobawala TP, et al. Deciphering the potential value of 5-fluorouracil metabolic enzymes in predicting prognosis and treatment response of colorectal cancer patients. Int J Biol Markers. 2018,33(2):180-188. doi: 10.1177/1724600817748539
    Read this paper