TIA1 antibody [TIA1/1313]

GeneTex

TIA1 antibody [TIA1/1313]

9

WB: 1-2microg/ml for 60 minutes at RT. ICC/IF: 1-2microg/ml. FACS: 0.5-1microg/106 cells in 0.1ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

TIA1/1313

0.2 mg/ml

Unconjugated

TIA1

TIA1 cytotoxic granule associated RNA binding protein

ALS26; nucleolysin TIA-1; nucleolysin TIA-1 isoform p40; p40-TIA-1 (containing p15-TIA-1); T-cell-restricted intracellular antigen-1; TIA-1; WDM

Mouse

IgG2b

Nucleolysin TIA-1 isoform p40

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203